QUEEN'S BIOLOGY MCIB SEMINAR SERIES
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Seminar series of the Molecular, Cellular & Integrative Biology
research groups at Queen's University

01.30.2018// Xiaolong Yang, Department of Pathology and Molecular Medicine, Queen's University

1/25/2018

 

Exploring Hippo signaling pathway by gene expression profile, proteomics, bioluminescent biosensor, and CRISPR technologies

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The Hippo signal pathway was originally identified in Drosophila and later in mammals as regulator of organ size in animals. Later studies showed that this pathway plays critical roles in a wide range of biological functions including development, tissue homeostasis, tumorigenesis, drug resistance, mechanotransduction, heart development and disease, and neuronal fate and dendrite tilling. In this talk, Dr. Yang will present findings from his lab in exploring the Hippo signalling pathway in various biological functions using gene expression profile (microarray, RNA-seq, and NanoString), proteomics (SILAC and Bio-ID), bioluminescent biosensor, and CRISPR gene editing functional genomics technologies.

11:30-12:30 BioSci Rm. 3110
And Free Lunch Meet & Greet 12:30-1:30 in BioSci 3rd floor lunch room (Rm 3406)

01.23.2018// Tariq Akhtar, Department of Molecular and Cellular Biology, University of Guelph

1/19/2018

 

Plant Polyisoprenoids – Secondary metabolites or physiologically important superlipids?

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Since the accidental discovery of polyisoprenoids in cellulose pulp extracts almost 60 years ago, the widespread occurrence of these compounds has been reported throughout the plant kingdom.   Yet, questions still remain about how plant polyisoprenoids are synthesized, where they reside in the cell and what functional role they serve.  This seminar will highlight some of our most recent findings about this historically enigmatic class of plant compounds and present evidence for a more evolutionary conserved role for polyisoprenoids than previously thought.

11:30-12:30 BioSci Rm. 3110
And Free Lunch Meet & Greet 12:30-1:30 in BioSci 3rd floor lunch room (Rm 3406)

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