QUEEN'S BIOLOGY MCIB SEMINAR SERIES
  • Home
  • Schedule
  • Contact

Seminar series of the Molecular, Cellular & Integrative Biology
research groups at Queen's University

Tues Jan 26 // Howard Teresinki // Snedden Lab, Queen's University

1/21/2021

 
Picture

Howard Teresinki
PhD Candidate, Snedden Lab, Queen's University
Identification and characterization of novel targets for a subfamily of Arabidopsis calmodulin-like (CML) proteins

​Calcium is a ubiquitous second messenger in signal transduction pathways of all eukaryotic cells. In plants, calcium signalling plays critical roles in a variety of developmental processes as well as during cellular responses to abiotic and biotic stress. The evolutionarily-conserved calcium sensor, Calmodulin (CaM), responds to calcium signals and, through protein-protein interactions in cells, facilitates downstream responses. Plants possess an additional and unique family of “calmodulin-like” (CML) calcium sensors which, in Arabidopsis thaliana, contains 50 members. Despite this expanded complexity, few of the binding partners and/or in vivo functions of CMLs are known. Here I present data from my PhD thesis demonstrating that CaM and a subfamily of biochemically unusual CMLs are capable of interacting with specialized structural domains from among three distinct and unrelated protein families in Arabidopsis. I utilised a combination of genetic, biochemical, and biophysical approaches to explore the physical properties and physiological  roles of CML interactions with these putative targets. Collectively, my data suggests novel functions for plant CMLs in gene regulation and cytoskeletal activity.

Comments are closed.

    Archives

    February 2021
    January 2021
    December 2020
    November 2020
    October 2020
    September 2020
    August 2020
    June 2020
    April 2020
    March 2020
    February 2020
    January 2020
    November 2019
    October 2019
    September 2019
    August 2019
    July 2019
    May 2019
    April 2019
    March 2019
    February 2019
    January 2019
    November 2018
    October 2018
    September 2018
    June 2018
    May 2018
    April 2018
    March 2018
    February 2018
    January 2018
    November 2017
    October 2017
    September 2017
    June 2017
    May 2017
    April 2017
    March 2017
    February 2017
    January 2017
    December 2016
    November 2016
    October 2016
    September 2016
    August 2016

Powered by Create your own unique website with customizable templates.
  • Home
  • Schedule
  • Contact